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Effect on the gastrointestinal absorption of drugs from different classes in the biopharmaceutics classification system, when treating with liraglutide

17 Saxagliptin is a reversible, potent inhibitor that is selective for DPP-4 by more than 4,000-fold, compared with sitagliptin, whose selectivity is more than 2,600-fold

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The IL-13R2, binds to IL-13 with high affinity but lacks a cytoplasmic domain thus does not signal downstream, however it may act as a negative regulator of IL-13 and IL-4 signaling

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