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According to the Global Burden of Disease Study 2021, ALS prevalence has increased by nearly 68% between 1990 and 2021, with incidence rising by 74.5% and associated DALYs by 105.5% [1]

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An international study combining single-cell genomics, spatial transcriptomics and artificial intelligence has identified large-scale changes in three-dimensional genome organisation in Alzheimers-affected brain cells, establishing chromatin architecture as a previously overlooked component of the diseases molecular pathology and a potential framework for future therapeutic targeting

In a study investigating the mechanism of this effect, researchers used pancreatic tissue fragments from normal and diabetic rats

Arsenic tolerance in Arabidopsis is mediated by two ABCC-type phytochelatin transporters