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This design choice introduces potential bias, particularly for subjective outcomes, but it reflects the practical reality that these treatments have different injection devices and titration schedules that would make blinding extremely difficult

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Silver (Ag) NPs with a size of 10 nm had higher tissue distribution and caused more severe hepatobiliary toxicity than larger NPs (40 and 100 nm) (Recordati et al., 2016)

Using a syringe calibrated in units, doses can be measured precisely, especially with proper technique

Bantun, Farkad