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During physical or cognitive exertion, the metabolic demand increases, naturally generating more ROS

Stability concerns mean that some percentage of the copper peptide oxidizes before reaching its target

This work was partially supported by the National Natural Science Foundation of China (82273961, 82073904, 81872915 to M.-W.W., 82273985, 82121005, 81973373 to D.Y., 32200576, 32071203 to L.-H.Z., 82121005 to H.E.X

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