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In this context, several sensors and pathways regulating the transcription factors, such as activator protein 1 (AP-1), cAMP response element-binding protein (CREB), hypoxia inducible factor-1 (HIF-1), nuclear factor B (NF-B), activating transcription factor 4 (ATF-4), and nuclear factor-erythroid 2-related factor-2 (Nrf2), have been described (Marinho et al

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7 The consequence of an endplate fracture is a possible defect healing which abrogates the function of the endplate for disc nutrition and thus promotes disc degeneration

Plant J 24:569-582 Grill ES, Loeffler E, Winnacker L, Zenk MH (1989) Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific -glutamylcysteine dipeptide transpeptidase (phytochelatin synthase)

M., Anders, R