In terms of chemicals, the plant has more than 200 different types of alkaloids, such as catharanthine, actineoplastidemeric, reserpine, raubasine, ajmalicine, Vinceine, vinneamine, raubasine, and more (89, 90)
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IC50 was 34.19 M, 61.53 M in the senescent fibroblasts from keloid and normal skin, and 93.77 M, 104.6 M in non-senescent control fibroblasts from keloid and normal skin, respectively