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Disruptions in these mechanisms following chronic cocaine use contribute to addiction, due, in part, to the unique architecture of the mesocortical pathway

nice.org.uk/guidance/ng247 Cozzolino M, Busnelli A, Pellegrini L, Riviello E, Vitagliano A

They also noted that GDF15 levels could rise to approximately 19,000 pg/mL during pregnancy 43

Exploiting the anti-biofilm effect of the engineered phage endolysin PM-477 to disrupt in vitro single- and dual-species biofilms of vaginal pathogens associated with bacterial vaginosis