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The mutations comprise of 57 amino acid substitutions (65.5%), one complete gene deletion (3, 306), one complete exon 1 deletion (16), one substitution at stop codon 255 resulting in a Serine residue (336), ten small deletions resulting in either a premature stop codon or in an in-frame amino acid residue deletion, four small insertions (335), nine nonsense mutations and four splice site mutations, resulting in aberrant splicing [Figure 12]

High prevalence of cerebral microbleeds at 7Tesla MRI in patients with early Alzheimers disease

households have pets, APPA finds in new survey

In CVD, the superoxide anion interacts with the nitric oxide free radical to generate peroxynitrite, which interrupts cardiovascular function

Spending in 2024 increased 5.7 percent compared to 2023, more than two percentage points above the 3.6 percent benchmark