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Effect of tranexamic acid on melasma: a clinical trial with histological evaluation

Revisiting Vitamin B12 Deficiency: A Clinicians Guide For the 21st Century.University of Virginia School of Medicine

Recently, an in vitro study by Yonezawa et al

Tranexamic acid is usually administered in melasma at a dosage of 250 mg twice daily (Shin et al., 2013) either monotherapy or in combination with other therapeutic options (Karn et al., 2012

46 However, the effects may vary at different stages of the disease, as evidenced by the study showing that the reduction was most pronounced in the early stages but less so in more advanced stages with behavioral symptoms