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August 1, 2025

Application of the Wnt/-catenin pathway in the clinic Constitutive activation and inactivation of the Wnt/-catenin pathway extensively participate in the physiopathological process of numerous diseases, indicating that this pathway has practical value in the clinic, particularly in the diagnosis, treatment, and prognosis of diseases

CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation

At the same time, microglia secrete inflammatory cytokines to produce inflammatory responses, further exacerbating the neurotoxicity [118]

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