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The altered autoregulation of blood flow cannot meet the metabolic demand of tissues in ME/CFS, leading to tissue hypoxia and subsequent ischaemia/reperfusion injury with its associated symptoms and signs ( Endothelial damage Endothelial cells are important regulators of the immune system (308)

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Concentration changes (1 mL or 3 mL BAC water instead of 2 mL) will change the per-dose draw volume but not the swab or syringe count

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