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The researchers suggested that adequate levels of glutathione and glutathione peroxidase might compensate or replace the deficient vitamin C in the carnitine biosynthesis pathway

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This is particularly important regarding rodenthuman differences, as rodents and rodent immune cells are commonly used to model human immune function

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Furthermore, in vivo administration of the antioxidant N-Acetyl-L-cysteine ethyl ester (NACET) increased the pool of reduced thiols and restored DUB activity in aged animals without altering glutathione levels