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JAMA Intern Med (2018) 178:1098

[DOI] [PubMed] [Google Scholar] 224.Tehran M.M., Kovanen P.T., Xu S., Jamialahmadi T., Sahebkar A

The project is supported by the Italian PNRR-MAD project (PNRR-MAD-2022-12375656)

Medications Both oral and topical medications can help relieve hand numbness, including: Over-the-counter medications: Includes ibuprofen and other nonsteroidal anti-inflammatory drugs to relieve pain Antidepressants and antiseizure: Treats neuropathic pain Topical treatments: Includes lidocaine patches and a capsaicin cream to ease mild pain and peripheral neuropathy 6

Furthermore, the results of some secondary analyses should be interpreted with caution due to wide confidence intervals stemming from the rarity of the outcomes