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however, the effect of tachyphylaxis on gastric emptying (especially with chronic use) remains unclear

Voon V, Fernagut P-O, Wickens J, Baunez C, Rodriguez M, Pavon N, et al

Evidence: The strongest data come from a large meta-analysis involving over 100,000 patients

Semaglutide represents a significant advancement in medical weight management, but success requires comprehensive lifestyle modification

This study innovatively focuses on the mechanism by which FOXO4-DRI induces apoptosis in senescent endothelial cells, demonstrating that it functions by activating the p53/BCL-2/Caspase-3 signaling pathway to promote selective apoptosis of these cells