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Se asocia con descensos del 82,4% de grasa heptica con normalizacin en el 86% con dosis semanal de 12mg en 24semanas, en relacin con la reduccin de tejido adiposo visceral, mejora de insulinosensibilidad, reduccin de leptina, aumento de adiponectina y evolucin favorable de parmetros del metabolismo lipdico y marcadores de fibrosis como Pro-C356

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We aim to assess weight loss, metabolic, and cardiovascular outcomes of 12 months of semaglutide

Sensitivity analysis and external validation of mediation pathway Additional sensitivity analyses confirmed that the identified mediation pathways related to body composition were not substantially biased by sex-specific effects ( Supplementary Figs

www.cdc.gov/diabetes/pdfs/ data/statistics/national-diabetes-statistics-report.pdf