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= 1.6) in the placebo group ( n = 3)

While GLP-1 medications can produce dramatic weight loss resultsoften 15-20% of body weight or morethe gut microbiome doesnt recover at the same pace

PMC6073405 Pickart L, Vasquez-Soltero JM, Margolina A

There additionally exists a safety argument for using MRAs in combination with SGLT2 inhibitors to reduce the risk of hyperkalemia, since the latter medication class has a modest potassium lowering effect as suggested by a recent post hoc analysis of MRA use in DAPA-HF [106]

While the results are promising, researchers emphasize that these benefits are still being studied and should not yet redefine prescribing practices