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What to Expect: Side Effects, Efficacy, and Timeline Most patients experience mild to moderate gastrointestinal side effects during the first 24 weeks of semaglutide, including nausea, constipation, and reduced appetite for foods they previously enjoyed

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Wipe the rubber stoppers of both vials thoroughly with alcohol wipes and allow them to air dry

Both GABA and serotonin availability declined with reduced receptor expression for GABA A 2 and GABAB1 in prefrontal cortex in the 2 week CMS (Tyagi et al., 2025)

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