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*Correspondence: Jianhua Zhang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

MANF reduces the expression of the pro-apoptotic factor CHOP by inhibiting the nuclear translocation of activating transcription factor 6 (ATF6), downregulating the generation of the XBP1s splice variant, and blocking activation of the PERK-eIF2 pathway [146]

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Sci Rep 7(1):113