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Research protocols using MK-677 require monthly HbA1c monitoring and immediate discontinuation if glucose dysregulation develops

Monitoring glucose levels, including fasting insulin and HbA1c, helps to assess metabolic health (1)

Furthermore, AMPK phosphorylates raptor in mTORC1, which down-regulates this complex [115]

Some researchers worry about misuse among people with or genetically disposed to having eating disorders, as preliminary data suggests more than 1 in 10 eating disorder patients also used Ozempic, an injection intended to treat diabetes