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And then there are some more serious reported side effects as well

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Mol Aspects Med 30:112 Frade J, Pope S, Schmidt M, Dringen R, Barbosa R, Pocock J, Laranjinha J, Heales S (2008) Glutamate induces release of glutathione from cultured rat astrocytes - a possible neuroprotective mechanism

Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebocontrolled, parallel-group study

No serious adverse effects were reported