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We additionally scored iPSC-derived hepatocytes for changes to fatty acid metabolic properties and found a decreased presence of neutral lipid droplets, concomitant with increased fatty acid -oxidation in the BWS lines, indicating alterations in the metabolic activity of BWS hepatocytes

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For laboratories, this subtype diversity is valuable because it enables structured experiments that map how a ligand behaves across a defined receptor landscape rather than assuming a single receptor state

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