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Second-Line Pharmacological Treatments Antidepressants Targeting Persistent Abdominal Pain Antidepressants are beneficial for IBS patients potentially due to their central effects, but most importantly due to their peripheral effects targeting underlying mechanisms, such as visceral hypersensitivity, pain perception, and motility (Ford et al., 2019)

This makes her one of the many celebrities over 50 who have admitted to GLP-1 use and seen positive results

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