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Recent large-scale single-cell transcriptomic atlases have already demonstrated the feasibility of systematically classifying glial cell diversity and revealed distinct astrocytes states across disease contexts 62,63,64

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Various cytokines, such as TGF-, SDF-1, and functional peptides, were employed to recruit endogenous stem cells to the damaged area and induce directional differentiation to achieve cell-free cartilage regeneration 48,49

Gene expression omnibus: NCBI gene expression and hybridization array data repository

PolterEJOnyeaghalaGLutseyPLFolsomARJoshuCEPlatzEAet al