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Some side effects (like nausea) are dose-dependent and might be milder at low doses, but others, like how it blunts appetite, could still lead to inadequate nutrient intake or a loss of lean muscle mass (called sarcopenia) if someone is losing weight without proper diet management
Gastroparesis (also known as stomach paralysis) is a chronic disease that affects the nerves and muscles in the stomach, interfering with the muscle activity (peristalsis), making stomach muscle contractions slower and weaker, slowing the movement of food through the stomach and small intestine and causing food not to be properly processed or emptied
Copper toxicity is a theoretical concern given that GHK-Cu chelates copper ions
Gevezova M, Minchev D, Pacheva I, Todorova T, Yordanova R, Timova E, Ivanov I, Sarafian V (2022) Association of NGF and mitochondrial respiration with autism spectrum disorder
121 However, CV risk reduction was not confirmed in a large prospective study of patients with T2D who were already receiving statin therapy, and there was suggestion of increased risk of stroke
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