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and Akkermansia spp., effectively moderating the microbial imbalance and colonic inflammation triggered by experimental colitis, alongside preserving the integrity of the mucus barrier ( Metformins impact on the gut microbiome also plays a role in metformins ability to fight tumors

However, under physiological conditions, GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4) ( 4.1 Mechanism of anti-inflammatory effects GLP-1 exhibits potent anti-inflammatory effects

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Conversely, supplementing with omega-3 fatty acids may reduce levels of inflammation and has been found to reduce acne severity (36)

Those affected who want to relieve their bodies, eat out or break away from their histamine-reduced diet can also take special preparations that supply the enzyme DAO in a targeted manner and thus quickly and easily support the body in breaking down histamine.