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The United Kingdom shows the weakest growth at 10.9% , just 1.3 points below the global average, shaped by tighter labeling restrictions and limited formulary coverage under NHS-linked channels

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To address this limitation, research has concentrated on many strategies, including identifying and developing DPP-IV inhibitors 43,44 , altering the structural makeup of GLP-1, searching for structural analogues that are more resistant to DPP-IV cleavage 45 , and increasing its hydrodynamic radius ( R h) above the glomerular filtration cutoff by conjugating it to proteins such as transferrin 46 , albumin 47 , and elastin-like polypeptides 48

Ju, H., Zou, R., Venema, V