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The second one is the fibrillar pattern, which includes pigmented furrows and fine cross-hatched strands

In fact, SODs are at the frontline of the defence against oxidants because they dismutate O 2 into molecular oxygen and H 2 O 2 , diminishing the concentration of O 2 the most dangerous free radical in all cell compartmentsand thus preventing OS (Figure 2) [6]

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In light of these findings, further development of cardiovascular therapeutics based on these natural metabolites is highly promising