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Furthermore, GPER enhances insulin responsiveness in adipose tissue, suppresses hepatic glucose production, and reduces blood glucose levels, further augmenting insulin sensitivity [4, 31]

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So you get these questions What is the research telling us

Because of their properties of neutralising reactive oxygen species, supplementation with antioxidants could be a potential treatment support option [7]

At the cellular level, these implications were posited to be related to the upregulation of actin fiber formation, as the researchers commented that F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157 exposed cells