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The cerebellum, despite its extensive connections with the rest of the brain, has received considerably less attention

This phenomenon, termed adaptive thermogenesis or metabolic adaptation, means the body requires fewer calories to maintain its new lower weight

Previous reports have shown that miR-483-3p functions as an oncogene by modulating multiple target genes in various human cancers 45 .In the present study, we reveal that miR-483-3p functions as a critical regulator of human NK cell cytotoxicity by directly targeting IGF-1

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Together, these trials included 3,377 adults with obesity or who were overweight