By framing metabolic reprogramming as a network-level target, this review offers a novel perspective on overcoming the specificity challenges that have hindered the clinical application of immunometabolism research
By binding to DC and P2RY2 receptor on the surface of macrophages, ATP promotes the infiltration of many myeloid cells into tumor areas (103)
In addition, previous studies have also suggested that increased levels of miR-4474 and miR-4717 in CRC tissues with positive infection of Fusobacterium nucleatum lead to decreases in the expression of CREB-binding protein (CBP), thereby promoting the progression of CRC (141)
The relationship between a high-fat diet, gut microbiome, and systemic chronic inflammation: insights from integrated multiomics analysis
Moreover, available information regarding the precise roles of JA in its simultaneous regulation of ROS and detoxification of MG under alkaline stress in crop plants is limited, and thus warrants in-depth investigation to understand how antioxidant metabolism changes in crop plants in response to Na 2 CO 3 induced-toxicity
