"B12 deficiency with neurological manifestations in the absence of anaemia"
Cagrilintide has similar GI tolerability, with one important difference: it causes more severe sickness at the start of treatment, which is thought to be because it strongly slows down stomach motility
(2) F Bes, W Hofman, J Schuur, and C Van Boxtel (1992) Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients
Heffernan, Jiang, Thorburn, and Ng reported in the American Journal of Physiology that oral administration of AOD9401 to ob/ob mice was associated with reduced body-weight gain, altered adipose lipogenic and lipolytic activity, and acute changes in energy expenditure, evidence that a growth-hormone C-terminal fragment could act after oral delivery in a rodent model [3]
The peptide selectively targets cells that have already undergone senescence as a consequence of earlier chemotherapy exposure, demonstrating a favorable safety profile for potential clinical application