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Model-agnostic interpretability methods, such as Shapley Additive Explanations and Local Interpretable Model-agnostic Explanations, help to unpack these complex models by quantifying the influence of individual input features on either specific predictions or overall model behavior

Williams DL, Munday P

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Phase I and Phase II applied to describe types of drug metabolism was first used in the 1940s.Phase II metabolism is terminology coined by RT Williams, whereby a compound is first subject tooxidation reduction or hydrolysis (Phase I reactions), which may be associated with bioactivation, andthen the functional group created is conjugated to a less toxic or inactive compound