Reversal of diet-induced obesity in mice The defining study, Neelakantan and colleagues in Biochemical Pharmacology (2018), reported that a potent methylquinolinium NNMT inhibitor reduced body weight, white-fat mass, adipocyte size and plasma cholesterol in diet-induced obese mice, without changing food intake or causing overt adverse findings [1]
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In the BPC157-treated groups, BPC157 was continuously intramuscularly administered for 7 days after modeling
Studies published in Biochemical Pharmacology show that NNMT expression increases significantly with aging in skeletal muscle tissue and correlates with impaired muscle stem cell function and reduced regenerative capacity
Legal status: Not FDA-approved for human use Sold as a "research chemical" Legal to buy and possess in most countries Widely used despite research-only labeling What BPC-157 does in your body The mechanism is elegantly simple
