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Here's what "optimal" actually looks like: TSH: 0.5 - 2.0 (metabolic efficiency) Free T3: Upper third of range (active thyroid hormone) Fasting insulin: Under 5 (insulin sensitivity) Vitamin D: 60 - 80 ng/mL (immune and hormonal function) Estradiol: 150 - 250 pg/mL in perimenopause (cognitive and metabolic support) If you're operating in "normal" ranges but experiencing symptoms, you're not crazy

it is not indicated for pediatric patients

Fecal microbiota transplantation considerably improves survival and reduces the incidence of abdominal infections in patients with liver failure [78, 79]

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Eli Lillys December 2025 press release reported average weight loss of up to 71.2 lbs at the highest dose, alongside substantial relief from osteoarthritis pain