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Dilokthornsakul et al

Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue, first described by Raun and colleagues in 1998 as the first selective growth hormone secretagogue. It remains one of the most extensively characterised compounds of its class in the published research literature

The latter could be the result of Tesamorelins ability to reduce visceral fat and preserve lean muscle

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Only the administration of insulin directly into the portal vein will really treat the metabolic derangement present in T1DM (Fig