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[4] This risk could potentially be compounded by dehydration from Wegovy-related gastrointestinal side effects

However, these approaches increase injection burden, multiply opportunities for measurement error, and deviate even further from studied protocols

Nonetheless, it should be acknowledged that in the context of a chronic disease that has reached epidemic proportions, data from randomized clinical trials aimed primarily at proving the efficacy of these drugs may have been insufficient to unveil all the safety issues

Spiazzi, MD, PhD, of Cleveland Clinic, and colleagues

These effects are generally mild and resolve over 3-4 weeks as the body becomes accustomed to the medication Gallstone formation and acute pancreatitis are a rare but potentially severe adverse effect from Ozempic (semaglutide) treatment, with the risk of developing pancreatitis estimated at 0.2-0.5% during clinical trials