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Oral versions such as capsules or troches are more convenient, but absorption through the digestive tract is far less consistent, so the amount that actually reaches circulation can vary widely

Collagen doesn't just decline with age

This hormonal imbalancelow progesterone alongside fluctuating or excessive estrogencan increase the production of thyroid-binding globulin (TBG), which binds thyroid hormones and reduces the availability of free T3, the active form of thyroid hormone

That gap widens over time, from roughly 4-5 percentage points at 24 weeks to over 6 percentage points by 68-72 weeks