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Ghrelin rebounds, gastric emptying returns to normal speed, and insulin support that the medication was providing withdraws over roughly the time it takes to clear the system, often while appetite is already climbing faster than eating patterns have adjusted
Garvey WT, Bluher M, Contreras CKO, et al
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This mechanism operates primarily through the stimulation of insulin release in response to elevated blood sugar levels while simultaneously suppressing glucagon release, which contributes to glucose production in the liver
M.MerrittC.SeydouxG.et al (2007a)
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