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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood

It catalyzes the dismutation of superoxide radical into oxygen and hydrogen peroxide [82]

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2.7 Solubility The general rule of solubility is that like dissolves like. This means that polar compounds tend to be soluble in polar solvents but insoluble in nonpolar solvents, and nonpolar compounds tend to be soluble in nonpolar solvents but insoluble in polar solvents