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Levothyroxine, which requires consistent absorption for stable thyroid hormone levels, may need dose adjustment or timing modification when used concurrently with this medication

Semaglutide is FDA-approved for multiple indications and is considered safe for use in both diabetics and non-diabetics [6, 55]

Clinical trials show average weight loss of 14.9% at the 2.4 mg dose over 68 weeks

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That is an NNT (Number Needed to Treat) of 67 over three years