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While substantial progress has been made in understanding these mechanisms, we also acknowledge the limitations of current research methodologies and call for further investigations to translate these findings into effective therapeutic strategies for individuals affected by ethanol-induced depression

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For example, in a prospective study aimed at investigating the influence of GLP-1RA and DPP4 inhibitors on the development of depression in patients with newly diagnosed T2DM, participants receiving incretin-based therapies displayed marked reduction of depressive symptoms after one year, when compared to the control group