Ongoing phase 3 trials are in progress, and CagriSema is currently under FDA review, with a decision expected in late 2026
The sensible approach as a consumer is to match an evidence-backed option to a clear goal, and to explore the less-proven ones one at a time, keeping in mind that they may not work, may not work for a given person, or may carry side effects or interactions with other medications
This is thought to have several effects: It may help muscles absorb glucose without needing insulin, build more mitochondria, burn fat, and reduce inflammation
~ AlphaMD Let's address the elephant in the room, or rather, the thing that gets smaller in the room
Suppression of proteoglycan synthesis: Steroids can also suppress proteoglycan synthesis, which is important for the extracellular matrix and collagen matrix fibrillinogenesis