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Meanwhile, small-molecule GLP-1 receptor agonists have garnered significant interest from multinational pharmaceutical companies due to their oral bioavailability and lower production costs

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49 ) to increase NAD + recycling and promote increases in mitochondrial-driven respiration, as shown by Seahorse XF analysis (Fig

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Copper interacts with the key aggregation-prone proteins associated with ALS, including TAR DNA binding protein 43 (TDP-43), CuZn-SOD, and fused in sarcoma (FUS)