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Dosage: 300-500 mcg daily via subcutaneous injection

Reasons to Get Your B-12 Shot Today B-12 is said to be effective in reducing stress levels, , maintaining healthy skin and boosting your energy levels

While this makes the measurement on the syringe larger and easier to see, it also means you are injecting more liquid into the subcutaneous tissue, which some find slightly less comfortable

On the other hand, oral supplements are processed through the digestive system, which might slow down absorption and the onset of benefits

Long-term use of metformin (for type 2 diabetes) or proton pump inhibitors can also deplete B12 levels over time