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After eight weeks of injections (23.5 months of age), mice were transitioned to receive MOTS-c injections three times weekly

Similarly, in the enteric nervous system, the loss of neurons is replenished by neurogenesis precursor cells that behave like stem cells and are prominent in the submucosal zone and in the muscular layers ( in vitro, that a selective estrogen receptor (ER) agonist, LY3201, stimulated glial-to-neuron cell differentiation