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Lastly, the synthetic mimics of seleno-GPxs appear to be an interesting strategy to develop radiation countermeasures

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Moreover, the increase in reactive oxygen species (ROS) and reactive nitrogen species (RNS) in endothelial cells due to systemic inflammation might alter claudins and occludins, which are critical structural components of the BBB

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As a research tool, BPC-157 does not correspond to any known endogenous receptor ligand but has demonstrated interactions with several signaling systems in preclinical models