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Intrinsic factor is efficient at absorbing a high percentage of a small dose of B12, but it becomes saturated after a meal containing an above-average amount of B12, and about 4 to 6 hours are required before it can efficiently absorb another dose (Institute of Medicine, 1998)
Therefore, developing more selective and less toxic delivery systems, such as mitochondrial-targeted nanoparticles, will be a key direction for future advancements
Stomatal responses to environmental factors
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