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34: 2136 Welling PG, Thomsen JH, Shug AL, et al

Among patients that are initiated on GLP1RA therapy, a substantial subset discontinues the drug within the first year due to side effects and financial burdens

The FDA cited insufficient human safety data, potential for immune reactions, and manufacturing impurity concerns as the bases for this classification

Patient reports are equally compelling

In non-Caucasians, the C677T variant increased migraine risk by 3-fold.[ref][ref] In North Indians, the A1298C variant was associated with the risk of migraines.[ref] Related article: Getting to the root genetic cause of migraines 7