doi: 10.6026/97320630013356 PMCID: PMC5712779 Molecular docking analysis of curcumin analogues with COX-2 Mario Rowan Sohilait, Harno Dwi Pranowo, and Winarto Haryadi Pain Med
Research shows reduction in gut permeability and systemic inflammatory markers
Despite these challenges, pursuing further investigation into antioxidant enzymes, specifically superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase 1 (GPX1), as well as inflammatory markers such as interleukin-6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor-alpha (TNF-), remains crucial
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Instead of oral glutathione, consider N-acetylcysteine (600mg twice daily), which provides the cysteine substrate for hepatic glutathione synthesis and has documented hepatoprotective effects in acetaminophen toxicity and non-alcoholic fatty liver disease