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It is not intended for cosmetic weight loss or to treat depression, though one of its components is an antidepressant

How They Work: Mechanism of Action Phentermine: Stimulating the Nervous System Phentermine works by stimulating the central nervous system, causing the release of norepinephrine, which helps suppress appetite

That might explain both experiences. What Is Anhedonia

GLP-1 RAs such as dulaglutide and liraglutide may lower the risk of depressive and anxiety symptoms in diabetic populations, particularly with prolonged use